Random USMLE Facts volume 5-10

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Random USMLE Facts volume 5-10:

USMLE Facts 1 USMLE Facts 2 USMLE Facts 3 USMLE Facts 4 USMLE Facts 5
USMLE Facts 6 USMLE Facts 7 USMLE Facts 8 USMLE Facts 9 USMLE Facts 10

When swinging from a tree with one hand, what structure might be damaged?

Lower trunk of the brachial plexus.

What drugs can be prescribed to counter the reflex tachycardia (and relative hypotension) caused by nitrates?

Beta-blockers because beta-blockers slow the conduction through the AV valve.

What causes aplastic crises in sickle cell patients?

B19 virus - non-enveloped single-stranded DNA virus.

What values are abnormal in adult respiratory distress syndrome (ARDS)?

Lung compliance, work of breathing, V/Q mismatch, and capillary permeability.

What are some findings in intestinal malabsorption?

Anemia, petechiae, bone pain, muscle wasting, hyperkeratosis, and tetany.

What are some causes of intestinal malabsorption?

Pancreatic exocrine insufficiency, intestinal mucosal defects, and bacterial proliferation.

What are some findings in pancreatic adenocarcinoma?

• Adenocarcinoma of the pancreas of the head: Courvoisier sign, weight loss, obstructive jaundice (pale stools, dark urine, etc).
• Adenocarcinoma in the pancreatic body or tail: these cancers become symptomatic after they invade the splanchnic plexus and cause midgastric abdominal pain.

What are some causes of pancreatic adenocarcinoma?

Age, smoking, diabetes mellitus, chronic pancreatitis, genetics.

What enzyme repairs damaged DNA after UV exposure?

UV endonuclease.

What is produced after DNA is exposed to ionizing radiation?

DNA fractures; repaired by re-ligation.

What is more important for screening tests - sensitivity or specificity or positive predictive value?


What are some findings in defective factor VII?

Normal bleeding time with increased PT and PTT. Some findings may include prolonged bleeding after tooth extraction, painful joint swelling following minor trauma, and enlarged liver.

What is the mechanism of action of tetrodotoxin?

Blocks voltage-gated sodium channels in nerve cell membranes, inhibiting the passive transport of sodium.

What are some findings in small intestinal and colonic atresias in neonates?

Small intestinal and colonic atresias in neonates can cause bilious vomiting after 24 hours, ischemia of the bowel, and apple green appearance of the associated bowel segment. Ileum is the most likely affected bowel segment.

What is the pathogenesis of alcohol-induced hepatic steatosis?

Alcohol-induced hepatic steatosis is related to a decrease in fatty acid oxidation secondary to excess NADH production by alcohol dehydrogenase and aldehyde dehydrogenase.

When is medial longitudinal fasciculus (MLF) lesion seen?

Multiple sclerosis. Medial longitudinal fasciculus (MLF) lesion is caused due to demyelination of axons resulting in axon denudation. Some other findings seen are:
• Depletion of oligodendrocytes.
• Accumulation of lipid-laden macrophages.
• Fibrillary astrocytes due to injury to astrocytes.
• Lymphocytic and macrophagic infiltration.

What is defective in xeroderma pigmentosum?


USMLE Facts 1 USMLE Facts 2 USMLE Facts 3 USMLE Facts 4 USMLE Facts 5
USMLE Facts 6 USMLE Facts 7 USMLE Facts 8 USMLE Facts 9 USMLE Facts 10

Additional Readings:

Random USMLE Facts

1. Random USMLE Facts volume 1-1
2. Random USMLE Facts volume 2-1
3. Random USMLE Facts volume 3-1
4. Random USMLE Facts volume 4-1
5. Random USMLE Facts volume 5-1
6. Random USMLE Facts volume 6-1
7. Random USMLE Facts volume 7-1
8. Random USMLE Facts volume 8-1
9. Random USMLE Facts volume 9-1
10. Random USMLE Facts volume 10-1
11. Random USMLE Facts volume 11-1
12. Random USMLE Facts volume 12-1

General and Systemic Examinations

1. General Examination for Internal Medicine
2. Jugular Venous Distention Workup
3. ER Chest Pain Workup
4. Format for Patient Presentation
5. Pulmonary Examination for Internal Medicine
6. Cardiac Examination for Internal Medicine
7. Abdominal Examination for Internal Medicine
8. Cranial Nerve Reflexes
9. Motor System Examination
10. Random Sensory System Facts
11. Random Stroke Facts

Medical Files & Presentations

1. USMLE Flashcards [Size: 1.9 MB; Format: MS Powerpoint]
2. Otitis Media in Children [Size: 5.4 MB; Format: MS Powerpoint]
3. Irritable Bowel Syndrome [Size: 170 kB; Format: MS Powerpoint]
4. Acid-Base Disturbance: Acidotic or Alkalotic? [Size: 427 kB; Format: PDF]
5. Thrombocytopenia [Size: 2.42 MB; Format: MS Powerpoint]
6. Are Face Transplants Ethical? [Size: 70.2 kB; Format: MS Powerpoint]

USMLE Step 2 CS Videos

1. Video of Cardiology Examination in a Clinical Setting
2. Video of Neurology Examination in a Clinical Setting
3. Video of Pulmonology Examination in a Clinical Setting
4. Video of Musculoskeletal Examination in a Clinical Setting
5. Video of Abdominal Examination in a Clinical Setting
6. Video of HEENT Examination in a Clinical Setting
7. Video and Description of Rinne Hearing Test
8. Video and Description of Weber Hearing Test

USMLE Laboratory (lab) Values

1. USMLE Blood Lab Values
2. USMLE Cerebrospinal Lab Values
3. USMLE Hematologic Lab Values
4. USMLE Sweat and Urine Lab Values

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Useful Medical Images & Diagrams (link opens in a new window)

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