Notes on Alveolar-Blood Gas Exchange

    Rahul's Noteblog     Notes on Pulmonology     Notes on Alveolar-Blood Gas Exchange

Factors affecting PCO₂:
• Alveolar ventilation: Inverse relation.
• Hyperventilation: Inverse relation.
• Hypoventilation: Direct relation.
• Metabolic rate: Direct relationship.

Factors affecting alveolar PO₂:
• Atmospheric pressure: Direct relationship.
• Fractional concentration of oxygen: Direct relationship.
• Alveolar pressure of CO₂: Inverse relationship.

Fick law of diffusion:
• Simple diffusion = gas exchange between alveolar and pulmonary capillary blood.
• Factors affecting rate of diffusion also affect rate of CO₂ and O₂ exchange.

Rate of diffusion affected by: surface area and thickness of membranes.
• Main factor affecting solubility is the diffusion constant of a gas.

Additional Reading:

Basic Pulmonology

1. Lung Mechanics
2. Alveolar-Blood Gas Exchange
3. Gas Transport and Regulation of Respiration
4. Four Causes of Hypoxemia

Related Topics

1. Histology of the Respiratory System
2. Upper and Lower Respiratory Disorders

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