Random USMLE Facts volume 12-10

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Random USMLE Facts volume 12-10:

USMLE Facts 1 USMLE Facts 2 USMLE Facts 3 USMLE Facts 4 USMLE Facts 5
USMLE Facts 6 USMLE Facts 7 USMLE Facts 8 USMLE Facts 9 USMLE Facts 10

Why does smooth muscle sensitivity to calcium increase in steady state under normal conditions?

Smooth muscle contracts when myosin light chain (MLCP) is phosphorylated by actions of myosin light chain kinase (MLCK). Also note that myosin light chain phosphatase (MLCP) activity can cause smooth muscle contraction without the troponin binding system. Thus, unlike contraction in skeletal muscle, contraction of smooth muscle requires myosin light chains.

What is rigor mortis?

• Stiffening of the body after death.
• Contractions start a few hours after death and are not followed by relaxation.
• ATP is required for relaxation and is deficient in a dead body.
• In a dead muscle, calcium is released into the sarcoplasm, causing muscle contraction.
• However, each step of the contraction cycle requires ATP.
• In a dead body, only contraction occurs without relaxation.

What are some differences between red and white muscle fibers?

• Red: slow twitch, high myoglobin, smaller, more blood, more mitochondria, high oxidative capacity; seen in muscles of marathon runners.
• White: fast twitch, low myoglobin, larger, less blood, less mitochondria; increased activity of glycolytic enzyme content, low oxidative capacity; seen in muscles of sprinters.

What is pseudogout?

• Pseudogout is a calcium pyrophosphate deposition disease (CPDD).
• Too much hydroxyapatite in blood.
• When examined under a polarized light, crystals appear as rhomboids with weak positive birefringence.
• When calcium pyrophosphate forms, calcium deposition takes place, and pseudogout results.
• Treatment consists of rest and anti-inflammatory drugs.

What is gout?

See: Notes on Musculoskeletal Disorders

What is osteoarthritis?

See: Notes on Musculoskeletal Disorders

USMLE Facts 1 USMLE Facts 2 USMLE Facts 3 USMLE Facts 4 USMLE Facts 5
USMLE Facts 6 USMLE Facts 7 USMLE Facts 8 USMLE Facts 9 USMLE Facts 10

Additional Readings:

Random USMLE Facts

1. Random USMLE Facts volume 1-1
2. Random USMLE Facts volume 2-1
3. Random USMLE Facts volume 3-1
4. Random USMLE Facts volume 4-1
5. Random USMLE Facts volume 5-1
6. Random USMLE Facts volume 6-1
7. Random USMLE Facts volume 7-1
8. Random USMLE Facts volume 8-1
9. Random USMLE Facts volume 9-1
10. Random USMLE Facts volume 10-1
11. Random USMLE Facts volume 11-1
12. Random USMLE Facts volume 12-1

General and Systemic Examinations

1. General Examination for Internal Medicine
2. Jugular Venous Distention Workup
3. ER Chest Pain Workup
4. Format for Patient Presentation
5. Pulmonary Examination for Internal Medicine
6. Cardiac Examination for Internal Medicine
7. Abdominal Examination for Internal Medicine
8. Cranial Nerve Reflexes
9. Motor System Examination
10. Random Sensory System Facts
11. Random Stroke Facts

Medical Files & Presentations

1. USMLE Flashcards [Size: 1.9 MB; Format: MS Powerpoint]
2. Otitis Media in Children [Size: 5.4 MB; Format: MS Powerpoint]
3. Irritable Bowel Syndrome [Size: 170 kB; Format: MS Powerpoint]
4. Acid-Base Disturbance: Acidotic or Alkalotic? [Size: 427 kB; Format: PDF]
5. Thrombocytopenia [Size: 2.42 MB; Format: MS Powerpoint]
6. Are Face Transplants Ethical? [Size: 70.2 kB; Format: MS Powerpoint]

USMLE Step 2 CS Videos

1. Video of Cardiology Examination in a Clinical Setting
2. Video of Neurology Examination in a Clinical Setting
3. Video of Pulmonology Examination in a Clinical Setting
4. Video of Musculoskeletal Examination in a Clinical Setting
5. Video of Abdominal Examination in a Clinical Setting
6. Video of HEENT Examination in a Clinical Setting
7. Video and Description of Rinne Hearing Test
8. Video and Description of Weber Hearing Test

USMLE Laboratory (lab) Values

1. USMLE Blood Lab Values
2. USMLE Cerebrospinal Lab Values
3. USMLE Hematologic Lab Values
4. USMLE Sweat and Urine Lab Values

Medical Images

Useful Medical Images & Diagrams (link opens in a new window)

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