Random USMLE Facts volume 7-9

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Random USMLE Facts volume 7-9:

USMLE Facts 1 USMLE Facts 2 USMLE Facts 3 USMLE Facts 4 USMLE Facts 5
USMLE Facts 6 USMLE Facts 7 USMLE Facts 8 USMLE Facts 9 USMLE Facts 10

What are the histological bone findings in rickets?

Osteoid matrix accumulations around trabeculae.

What is the significance of reduced FEV1?

Obstructive pulmonary process.

What cells are active in histoplasma capsulatum infection?

Macrophages (they contain ovoid cells). Histoplasma capsulatum produces pulmonary infection in immunocompromised or HIV+ patients.

What does niacin do to anti-hypertensive medications?

It potentiates their effects.

What does niacin do to diabetic medications?

It depresses their effects.

What role does E. coli play in benign prostatic hyperplasia?

Benign prostatic hyperplasia produces urosepsis, and a complication of urosepsis is septic shock from E. coli infection.

What are the corresponding distribution values of drugs that are:

• Highly charged or has large molecular weight or is extensively bound to proteins: 3-5 liters.
• Small molecular weight or hydrophilic: 14-16 liters.
• Small molecular weight and uncharged (hydrophobic or lipophilic): 41 liters.
* Drugs bound to tissue display the highest volumes of distribution.

What nerve is damaged when an intramuscular injection is placed in the superomedial quadrant of the buttock?

Superior gluteal nerve.

How is Number Needed To Treat calculated?

NNT = 1/ARR.

How is ARR calculated?

ARR = absolute reduction rate = event rate (placebo) - event rate (treatment).

How is event rate calculated?

Event rate = disease occurrences / total population at risk.

In collage biosynthesis, what processes occur inside a fibroblast?

Hydroxylation (of proline and lysine residues), glycosylation (of lysine residues), disulfide bond formation, hydrophobic N-terminal signal cleavage, and assembly (or pro and alpha chains into triple helix).

Why do muscarinic antagonists need the vagus nerve?

When the vagus nerve is stimulated, acetylcholine is released, and muscarinic antagonists block the effects of acetylcholine at muscarinic receptors. However, if there is no vagus nerve (as in vagectomized individuals) muscarinic antagonists would be useless.

What is the mechanism of action of streptomycin?

Binding to 30s ribosome, inhibiting initiation of protein synthesis, and initiation complex formation.

How is oral bioavailability calculated?

Analyzing the graph of plasma concentration versus time and then applying the formula: [area under oral curve x IV dose] / [area under IV curve x oral dose].

What are the components of MEN I?

Parathyroid tumor, pituitary adenoma, pancreas tumor. There may be a VIPoma.

What are the components of MEN II A?

Medullary carcinoma of the thyroid, pheochromocytoma, parathyroid tumor.

What are the components of MEN II B?

Medullary carcinoma of the thyroid, pheochromocytoma, marfanoid habitus.

What are the findings in mitochondrial encephalomyopathy?

This disease displays mitochondrial inheritance. Findings include neuromuscular lesions, ragged red skeletal muscle fibers, and lactic acidosis in affected family members. Tissues with highest metabolic rates - muscle, neural, etc., are affected.

USMLE Facts 1 USMLE Facts 2 USMLE Facts 3 USMLE Facts 4 USMLE Facts 5
USMLE Facts 6 USMLE Facts 7 USMLE Facts 8 USMLE Facts 9 USMLE Facts 10

Additional Readings:

Random USMLE Facts

1. Random USMLE Facts volume 1-1
2. Random USMLE Facts volume 2-1
3. Random USMLE Facts volume 3-1
4. Random USMLE Facts volume 4-1
5. Random USMLE Facts volume 5-1
6. Random USMLE Facts volume 6-1
7. Random USMLE Facts volume 7-1
8. Random USMLE Facts volume 8-1
9. Random USMLE Facts volume 9-1
10. Random USMLE Facts volume 10-1
11. Random USMLE Facts volume 11-1
12. Random USMLE Facts volume 12-1

General and Systemic Examinations

1. General Examination for Internal Medicine
2. Jugular Venous Distention Workup
3. ER Chest Pain Workup
4. Format for Patient Presentation
5. Pulmonary Examination for Internal Medicine
6. Cardiac Examination for Internal Medicine
7. Abdominal Examination for Internal Medicine
8. Cranial Nerve Reflexes
9. Motor System Examination
10. Random Sensory System Facts
11. Random Stroke Facts

Medical Files & Presentations

1. USMLE Flashcards [Size: 1.9 MB; Format: MS Powerpoint]
2. Otitis Media in Children [Size: 5.4 MB; Format: MS Powerpoint]
3. Irritable Bowel Syndrome [Size: 170 kB; Format: MS Powerpoint]
4. Acid-Base Disturbance: Acidotic or Alkalotic? [Size: 427 kB; Format: PDF]
5. Thrombocytopenia [Size: 2.42 MB; Format: MS Powerpoint]
6. Are Face Transplants Ethical? [Size: 70.2 kB; Format: MS Powerpoint]

USMLE Step 2 CS Videos

1. Video of Cardiology Examination in a Clinical Setting
2. Video of Neurology Examination in a Clinical Setting
3. Video of Pulmonology Examination in a Clinical Setting
4. Video of Musculoskeletal Examination in a Clinical Setting
5. Video of Abdominal Examination in a Clinical Setting
6. Video of HEENT Examination in a Clinical Setting
7. Video and Description of Rinne Hearing Test
8. Video and Description of Weber Hearing Test

USMLE Laboratory (lab) Values

1. USMLE Blood Lab Values
2. USMLE Cerebrospinal Lab Values
3. USMLE Hematologic Lab Values
4. USMLE Sweat and Urine Lab Values

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Useful Medical Images & Diagrams (link opens in a new window)

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