Notes on Positive-sense RNA viruses

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Calicivrus:

• Naked; icosahedral.

• Norwalk: viral gastroenteritis in school-age kids; also in adults.

• Hepatitis E.

Picornavirus:

• Naked.

• Polio: sabin/live and salk/killed vaccines; poliomyelitis paralysis results from damaged anterior horn motor neurons.

• Echoviruses: aseptic meningitis.

• Enteroviruses: doesn't cause diarrhea.

• Rhinovirus: common cold.

• Coxsackie A: hand-foot-mouth disease; herpangina, aseptic meningitis, acute lymphoglandular pharyngitis, common cold.

• Coxsackie B: Bornholm's disease; illness in newborns, insulin-dependent diabetes in children, myocarditis.

• Hepatitis A.

Flavivirus:

• Enveloped.

• Yellow fever virus: mosquito-borne; liver, kidney, heart, GI damage.

• Dengue virus: hemorrhagic shock syndrome.

• St. Louis encephalitis virus: elderly - especially the ones with hypertension.

• Hepatitis C.

Togavirus:

• Enveloped.

• Rubella: crosses placenta; vaccine part of MMR.

• Venezuelan encephalitis, WEE, EEE: mosquito-borne; birds are reservoirs.

Coronavirus:

• Enveloped.

• Coronaviruses; second-most cause of common cold.

Retrovirus:

• Enveloped.

• HIV (Lentivirus group), HTLV (Oncovirus group), and sarcoma.

NOTE: All single-stranded except reovirus.

Additional Readings:

Basic Virology

1. Immune defences against viruses
2. Viral Hepatitis
3. DNA viruses
4. Positive-sense RNA viruses
5. Human Immunodeficiency Virus
6. Negative sense RNA viruses
7. Double stranded RNA Viruses
8. Viruses associated with cancer
9. Generalized vs specialized transduction
10. Hepatitis serologic markers
11. Bacterial vs viral infections
12. Human Immunodeficiency Virus (HIV) Infections and AIDS
13. Steps When Patient is Newly Diagnosed with HIV

Related Topics

1. Prenatal Infections

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