Notes on Positive-sense RNA viruses

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All ss except reovirus.

Calicivrus:
• Naked; icosahedral.
• Norwalk: viral gastroenteritis in school-age kids; also in adults.
• Hepatitis E.

Picornavirus:
• Naked.
• Polio: sabin/live and salk/killed vaccines; poliomyelitis paralysis results from damaged anterior horn motor neurons.
• Echoviruses: aseptic meningitis.
• Enteroviruses: doesn't cause diarrhea.
• Rhinovirus: common cold.
• Coxsackie A: hand-foot-mouth disease; herpangina, aseptic meningitis, acute lymphoglandular pharyngitis, common cold.
• Coxsackie B: Bornholm's disease; illness in newborns, insulin-dependent diabetes in children, myocarditis.
• Hepatitis A.

Flavivirus:
• Enveloped.
• Yellow fever virus: mosquito-borne; liver, kidney, heart, GI damage.
• Dengue virus: hemorrhagic shock syndrome.
• St. Louis encephalitis virus: elderly - especially the ones with hypertension.
• Hepatitis C.

Togavirus:
• Enveloped.
• Rubella: crosses placenta; vaccine part of MMR.
• Venezuelan encephalitis, WEE, EEE: mosquito-borne; birds are reservoirs.

Coronavirus:
• Enveloped.
• Coronaviruses; second-most cause of common cold.

Retrovirus:
• Enveloped.
• HIV (Lentivirus group), HTLV (Oncovirus group), and sarcoma.

Additional Readings:

Basic Virology

1. Immune defences against viruses
2. Viral Hepatitis
3. DNA viruses
4. Positive-sense RNA viruses
5. Human Immunodeficiency Virus
6. Negative sense RNA viruses
7. Double stranded RNA Viruses
8. Viruses associated with cancer
9. Generalized vs Specialized Transduction

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Page accessed on: July 29, 2010, 11:20 am.

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