Notes on Antidiuretic Hormone (ADH) and ECF Regulation

    Rahul's Noteblog     Notes on Endocrinology     Notes on Antidiuretic Hormone (ADH) and ECF Regulation

Introduction:
• ADH controls water excretion and ECF volume.
• Synthesized in hypothalamus; released by posterior pituitary.
• Acts on collecting ducts of kidneys.
• Increases water absorption in kidney.
• Decreased synthesis during weightlessness and after consumption of alcohol.

ADH secretion and effects:
• Diabetes insipidus: no effect of ADH; elevated extracellular osmolarity, but dilute, glucose-free urine production.
• Central neurogenic diabetes insipidus: no sufficient ADH.
• Peripheral diabetes insipidus: kidneys insensitive to ADH.

Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH):
• Excessive ADH secretion causes excessive water reabsorption in renal collecting duct.

Atrial Natriuretic Peptide:
• Released from right atrium of heart.
• Increased due to: stretch, and increased Na.
• Causes: H2O and Na loss by kidney.
• Increased secretion in weightlessness.

Additional Readings:

Basic Endocrinology

Introduction to Endocrinology
1. Hypothalamic-pituitary system
2. Adrenal Hormones
3. Antidiuretic Hormone (ADH) and ECF Regulation
4. Endocrine Pancreas
5. Growth Hormone
6. Adrenal Medulla
7. Hormonal Control of Calcium and Phosphate
8. Thyroid Hormones
9. Hormones of Male Reproduction
10. Hormones of Female Reproduction
11. Fluid Compartments of the Body
12. Notes on Hypothalamus Anterior Pituitary and Thyroid
13. Additional Notes on Female Reproduction
14. Hormonal Signaling Pathways

Related Topics

1. Histology of the Endocrine System
2. Histology of the Male Reproductive System
3. Histology of the Female Reproductive System

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