Antidiuretic Hormone (ADH) and ECF Regulation

  >   Rahul's Noteblog   >   Notes on Endocrinology   >   Antidiuretic Hormone (ADH) and ECF Regulation

ADH Secretion and Action:

• ADH controls water excretion and ECF volume.

• Synthesized in hypothalamus; released by posterior pituitary.

• Acts on collecting ducts of kidneys.

• Increases water absorption in kidney.

• Decreased synthesis during weightlessness and after consumption of alcohol.

ADH-Induced Disease:

• Diabetes insipidus: no effect of ADH; elevated extracellular osmolarity, but dilute, glucose-free urine production.

• Central neurogenic diabetes insipidus: no sufficient ADH.

• Peripheral diabetes insipidus: kidneys insensitive to ADH.

Syndrome of Inappropriate Antidiuretic Hormone secretion (SIADH):

• Excessive ADH secretion causes excessive water reabsorption in renal collecting duct.

Atrial Natriuretic Peptide:

• Released from right atrium of heart.

• Increased due to: stretch, and increased Na.

• Causes: H2O and Na loss by kidney.

• Increased secretion in weightlessness.

Additional Readings:

Basic Endocrinology

1. Introduction to Endocrinology
2. Hypothalamic-pituitary system
3. Adrenal Hormones
4. Antidiuretic Hormone (ADH) and ECF Regulation
5. Endocrine Pancreas
6. Growth Hormone
7. Adrenal Medulla
8. Hormonal Control of Calcium and Phosphate
9. Thyroid Hormones
10. Hormones of Male Reproduction
11. Hormones of Female Reproduction
12. Fluid Compartments of the Body
13. Notes on Hypothalamus Anterior Pituitary and Thyroid
14. Additional Notes on Female Reproduction
15. Hormonal Signaling Pathways
16. FAQ on Adrenal Hormones
17. FAQ on Male Reproduction
18. Synthesis and Deficiencies of Adrenal Hormones
19. Significance of Glycosylated Hemoblogin (HbA1c)
20. Significance of Measuring Albumin while with Calcium Levels
21. Stepwise Approach to Treatment of Ascites
22. How to differentiate between Diabetes Insipidus vs Psychogenic Polydipsia

Related Topics

1. Histology of the Endocrine System
2. Histology of the Male Reproductive System
3. Histology of the Female Reproductive System

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