Notes on Immunology Laboratory Technology

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Antigen-antibody Interactions:

• In the beginning, patient is in a state of antigen excess; Ab development has not yet begun.

• Then comes the equivalence zone: Abs are produced and bind to antigens, so neither Abs nor antigens are detected in blood.

• Finally comes the Ab excess zone; more-than-necessary Ab is produced.

Eg., Hepatitis B Infection:

• HBsAg and HBeAg antigens freely detected in blood.

• Then comes the window period: Abs are produced and bind to antigens, so neither Abs nor antigens are detected in blood.

• Finally comes the Ab excess zone; HBsAb and HBeAb excess rise in blood.

Additional Readings:

Basic Immunology

1. Introduction to Immunology
2. Cells of Immunology
3. Selection of Lymphocytes
4. Primary Response to Antigen
5. Antigen Processing and Presentation
6. Humoral Effector Mechanism Generator
7. Cell-Mediated Effector Mechanism Generator
8. Vaccination and Immunotherapy
9. Immunodeficiency Diseases
10. Acquired Immunodeficiency Syndrome
11. Hypersensitivities and Autoimmunity Diseases
12. Immunology of Transplantation
13. Immunology of Cancer
14. Immunology Laboratory Technology
15. Acquired Immunity
16. Type II Hypersensitivity Reaction
17. Hypersensitivity Reactions
18. Primary Immunodeficiency
19. Secondary Immunodeficiency
20. Type III Hypersensitivity Reaction
21. Type IV Hypersensitivity Reaction
22. Type V Hypersensitivity Reaction
23. Tumor Immunology
24. Images of Antibodies
25. Th1 vs Th2 cells

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1. Histology of Lymphoid Tissue

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