Type V Hypersensitivity Reaction

  >   Rahul's Noteblog   >   Notes on Immunology   >   Type V Hypersensitivity Reaction

What is Type V Hypersensitivity Reaction?

• These reactions occur when IgG class antibodies directed towards cell surface antigens have a stimulating effect on their target.

• Cells are signaled by agents such as hormones.

Amino acid-based hormones:

• These hormones cannot pass through plasma membranes because they are polar.

• They need a two-messenger system to gain entry into a cell.

• These depend on first and second messengers (eg., cyclic AMP).

• A single hormone molecule can result in the formation of several second messengers.

Toxic Shock Syndrome:

• HYPOTENSION, HYPOXIA, OLIGURIA, MICROVASCULAR.

• Defective innate immune system.

Mechanism of Toxic Shock Syndrome:

• Gram-negative bacteria - > septicemia LPS and endotoxins -> activated macrophages and endothelial cells -> release of TNG, IL1/6, and reactive oxyten intermediates.

• Gram-positive bacteria -> septic shock TNF synthesis, Peptidoglycan mediated aggregation of platelets, DIC.

Adult respiratory distress syndrome:

• Levels of lipopolysaccharide and cytokines increases.

• Neutrophil invasion of the lungs.

• Nitric Oxide, lipopolysaccharide; PLATELETS RELEASE THROMBAXANE and PROSTAGLANDINs; DISSEMINATED INTRAVASCULAR COAGULATION.

Additional Readings:

Basic Immunology

1. Introduction to Immunology
2. Cells of Immunology
3. Selection of Lymphocytes
4. Primary Response to Antigen
5. Antigen Processing and Presentation
6. Humoral Effector Mechanism Generator
7. Cell-Mediated Effector Mechanism Generator
8. Vaccination and Immunotherapy
9. Immunodeficiency Diseases
10. Acquired Immunodeficiency Syndrome
11. Hypersensitivities and Autoimmunity Diseases
12. Immunology of Transplantation
13. Immunology of Cancer
14. Immunology Laboratory Technology
15. Acquired Immunity
16. Type II Hypersensitivity Reaction
17. Hypersensitivity Reactions
18. Primary Immunodeficiency
19. Secondary Immunodeficiency
20. Type III Hypersensitivity Reaction
21. Type IV Hypersensitivity Reaction
22. Type V Hypersensitivity Reaction
23. Tumor Immunology
24. Images of Antibodies
25. Th1 vs Th2 cells

Related Topics

1. Histology of Lymphoid Tissue

Medical Images

Useful Medical Images & Diagrams (link opens in a new window)

Random Pages:

Life in a Drop of Water Review of Delta Roma Imperiale Fountain Pen
Video of me playing Titanic Piano Theme: The Portrait Notes on Cell Components
Notes on Osteology of Pectoral Region Notes on Enterococcus
Notes on Citric Acid Cycle and Glyoxylate Cycle Causes and Complications of Arteriovenous Fistulas
Significance of Measuring Albumin while with Calcium Levels Notes on Hypothalamic-pituitary system
Notes on Basic Gastrointestinal Physiology Life in a Drop of Water
Why is it hard to find Christian husbands? What is an ELEK`s Test?
Why did I decide to become a doctor? Medical School Admissions Essay Video: Titanic Piano Theme: The Portrait
Corporate Failure: The Enron Case My Experience during the Iraqi Invasion of Kuwait
USMLE Blood Lab Values Regulation of Heart Rate by Autonomic Nervous System
Images of Antibodies Video of me playing Unknown Easy Blues Piano
Notes on Integument Differentiation and Anatomy of a Blastocyst
Notes on Cell Components Notes on Nervous Tissue
Voices from Hell: My Experience in Mussoorie, India Video of Cardiology Examination in a Clinical Setting

Please Do Not Reproduce This Page

This page is written by Rahul Gladwin. Please do not duplicate the contents of this page in whole or part, in any form, without prior written permission.