Notes on Bacillus

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Genus: Bacillus.
• Gram +; spore forming; aerobic.

B. anthracis.
• Capsule is polypeptide (poly-D-glutamate).

• Found in animals, skins, and soil.

• Transmission: inhalation of spores or contact with infected animal.

Pathogenesis:
• Capsule inhibits phagocytosis.

Anthrax toxin:
Three protein parts:
• Protective antigen: mediates LF/EF entry.
• Lethal factor: kills cells.
• Edema factor: is an adenylate cyclase.

Diseases:
• Anthrax, cutaneous anthrax and pulmonary anthrax (Wool Sorter's Disease).

Treatment: ciprofloxacin or doxycycline.

• Vaccinations available.

B. cereus.
• Spores cause food poisioning.
• Emetic toxin (fast): diarrhea and vomiting.
• Diarrheal toxin (slow): watery diarrhea.

Additional Readings:

Basic Bacteriology

1. General Microbiology
2. Growth Medias and Oxygen Requirements
3. Staphylococus
4. Streptococcus
5. Enterococcus
6. Bacillus
7. Listeria
8. Corynebacterium
9. Actinomyces
10. Nocadria
11. Mycobacterium
12. Clostridium
13. Neisseria
14. Pseudomonas
15. Legionella
16. Bordetella
17. Francisella
18. Brucella
19. Campylobacter
20. Escherichia
21. Shigella
22. Klebsiella
23. Salmonella
24. Yersinia
25. Proteus
26. Vibrio
27. Pasteurella
28. Haemophilus
29. Bacteriodes and Prevotella
30. Treponema
31. Borrelia
32. Rickettsia
33. Coxiella
34. Ehrlichia
35. Chlamydia
36. Mycoplasma
37. What is an ELEK's Test?
38. Causes of Orchitis

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Page accessed on: September 10, 2010, 7:04 pm.

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