Notes on Mycoplasma

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Genus: Mycoplasma.
• Smallest free living bacteria.
• No cell wall - missing peptidoglycan.

• M. pneumoniae. (Eaton's agent).
• Extracellular, tiny, flexible; cannot be Gram-stained.
• No cholesterol synthesis.

• Found in human respiratory.

• Transmitted by respiratory droplets.

Pathogenesis:
• Attached to respiratory epithelium using P1 protein.
• Inhibits ciliary action.
• Produces H2O2, superoxide radicals, and cytolytic enzymes.

Diseases:
• Pneumonia.

Lab:
• Fried egg colonies on Mycoplasma or Eaton's media.
• + cold agglutinins test works 65% of time.

Treatment:
• Erythromycin, azithromycin, clarithromycin.

Ureaplasma urealyticum:
• Urease maker; urethritis; can cause renal calculi.

Additional Readings:

Basic Bacteriology

1. General Microbiology
2. Growth Medias and Oxygen Requirements
3. Staphylococus
4. Streptococcus
5. Enterococcus
6. Bacillus
7. Listeria
8. Corynebacterium
9. Actinomyces
10. Nocadria
11. Mycobacterium
12. Clostridium
13. Neisseria
14. Pseudomonas
15. Legionella
16. Bordetella
17. Francisella
18. Brucella
19. Campylobacter
20. Escherichia
21. Shigella
22. Klebsiella
23. Salmonella
24. Yersinia
25. Proteus
26. Vibrio
27. Pasteurella
28. Haemophilus
29. Bacteriodes and Prevotella
30. Treponema
31. Borrelia
32. Rickettsia
33. Coxiella
34. Ehrlichia
35. Chlamydia
36. Mycoplasma
37. What is an ELEK's Test?
38. Causes of Orchitis

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Page accessed on: September 10, 2010, 6:57 pm.

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