Notes on Chlamydia

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Genus: Chlamydia.

• Wall lacks muramic acid; cannot be Gram stained.

• Cannot make ATP.

• Obligate intracellular bacteria.

Chlamydia trachomatis.

• Actively replicate within cells.

• Infective form: inactive extracellular body.

• Found in human genital tract and eyes.

• Transmitted by sexual contact, and birth canal; hand to eye transmission.

Pathogenesis:

• Infection of mucosal cells leads to granulomatous response and damage.

Diseases:

• STDs (PID, cervicitis, urethritis).

• Lymphogranuloma venereum.

• Trachoma (causes blindness).

Lab:

• Cultured in tissue cultures or embryonated eggs.

• Cytoplasmic inclusions seen on Giemsa, iodine, and fluorescent Ab stained smears.

Treatment:

• Doxycycline or azithromycin.

Chlamydia pneumoniae.

• Respiratory infections.

Chlamydia psittaci.

• Found in birds.

• Transmitted by dust of dried bird feces.

• Intracellular growth.

• Causes Psittacosis (atypical pneumonia).

• Lab: Cytoplasmic inclusions seen on Giemsa, and fluorescent Ab stained smears.

• Treatment: doxycycline.

Additional Readings:

Basic Bacteriology

1. Bacterial Locations and Toxins
2. Growth Medias and Oxygen Requirements
3. Staphylococus
4. Streptococcus
5. Enterococcus
6. Bacillus
7. Listeria
8. Corynebacterium
9. Actinomyces
10. Nocadria
11. Mycobacterium
12. Clostridium
13. Neisseria
14. Pseudomonas
15. Legionella
16. Bordetella
17. Francisella
18. Brucella
19. Campylobacter
20. Escherichia
21. Shigella
22. Klebsiella
23. Salmonella
24. Yersinia
25. Proteus
26. Vibrio
27. Pasteurella
28. Haemophilus
29. Bacteriodes and Prevotella
30. Treponema
31. Borrelia
32. Rickettsia
33. Coxiella
34. Ehrlichia
35. Chlamydia
36. Mycoplasma
37. What is an ELEK's Test?
38. Causes of Orchitis
39. What is Leprosy?
40. What is Folliculitis?
41. What is Botulism?
42. How to interpret PPD (Purified Protein Derivative) results?
43. Prenatal Infections

Related Topics

1. Bacterial vs viral infections

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